重组胰岛素样生长因子结合蛋白3抗原

Description

Product name Recombinant human IGFBP3 with a fusion protein

Known as Insulin-like growth factor-binding protein 3; IBP-3; IGF-binding protein 3

Expression system E.coli

Tags His tag C-terminus

Specifications

SDS-PAGE 87 kDa, reducing conditions

Purity >95% SDS-PAGE

Form Lyophilized powder

Stability and Storage

Storage Store at -20 ~ -80℃, avoid repeated freeze/ thaw cycle

Stability Aliquot and store at –20℃ for 12 months.

Constituents Lyophilized from 0.22 μm filtered solution in Tris-HCl with 0.2M NaCl, pH8.

General information

Function IGF-binding proteins prolong the half-life of the IGFs and have been shown to

either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.

They alter the interaction of IGFs with their cell surface receptors. Also exhibits

IGF-independent antiproliferative and apoptotic effects mediated by its receptor

TMEM219/IGFBP-3R.

Images

Human IGFBP3 with a fusion protein on SDS-PAGE

under reducing condition(R). The gel was visualized by

Coomassie® Blue Staining. The purity of the protein is

greater than 95%.