重组可溶性生长刺激表达基因2蛋白抗原

 Description

Product name

Recombinant human sST2 protein (His tag)

Known as

Interleukin-1 receptor-like 1; Protein ST2

Expression system

HEK 293 cells

Tags

His tag C-terminus

Specifications

SDS-PAGE

36.8 kDa, reducing conditions

Purity

>95% SDS-PAGE

Form

Lyophilized powder

Stability and Storage

Storage

Store at -20 ~ -80℃, avoid repeated freeze/ thaw cycle

Stability

Store at –20℃ for 12 months, or reconstitute for 3 months.

Constituents

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4.

General information

Function

Receptor for interleukin-33 (IL-33); signaling requires association of the coreceptor IL1RAP. Upon tissue injury, induces UCP2-dependent mitochondrial rewiring that attenuates the generation of reactive oxygen species and preserves the integrity of Krebs cycle required for persistent production of itaconate and subsequent GATA3-dependent differentiation of inflammation-resolving alternatively activated macrophages.

Images

Human sST2 (His Tag) on SDS-PAGE under reducing condition(R). The gel was visualized by Coomassie®Blue Staining. The purity of the protein is greater than 95%.